Neglected benefits
The researchers, led by epidemiologist Ziyad Al-Aly at the St. Louis VA, also looked at MACE and deaths without documented COVID-19 cases. Here, the benefits of COVID-19 vaccines were stronger, suggesting COVID-19 cases may have been missed or undiagnosed. The shots appeared to drop the rate of MACE from 382 per 10,000 to 358, and the rate of death from 223 to 207.
“Extrapolating these estimates to a population of 1 million people, vaccination could plausibly be associated with averting approximately 2,370 MACE events and 1,580 deaths over an 8-month period,” the researchers note, though they urge caution in interpreting the finding.
The study has limitations, including
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